Article

Clinical and molecular characteristics, transcriptome, and drug efficacy of ERBB2 tyrosine kinase and non-tyrosine kinase mutations in non-small cell lung cancer

2023-07-28

Abstract excerpt

ERBB2 mutations in the tyrosine kinase domain (TKD) have been widely reported in non-small cell lung cancer (NSCLC). More and more non-tyrosine kinase domain (non-TKD) mutations of ERBB2 have been detected. However, the clinical effects of non-TKD mutations are still unknown. Therefore, this study aims to study the molecular and clinical characteristics, transcriptome differences, and sensitive drugs of TKD and no...

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Literature Corpus work: e1f8bc78-058d-5050-92d9-08da19f6aac2
DOI: 10.21203/rs.3.rs-3149860/v1

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