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Synaptopodin-2: a potential tumor suppressor

7 Aug 2023

Abstract excerpt

Initially identified as an actin-binding protein containing a PSD95-DLG-ZO1 Domain (PZD domain), Synaptopodin 2 (SYNPO2) has long been considered a structural protein ubiquitously expressed in muscular tissues. However, emerging evidence suggests that SYNPO2 performs diverse functions in cancers in addition to its role in microfilament assembly. In most cancers, high SYNPO2 expression is positively correlated...

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Autophagy in Disease and Therapy
Hippo pathway signaling and YAP/TAZ
Ubiquitin and proteasome pathways

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37544991
DOI: 10.1186/s12935-023-03013-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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