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Archival influenza virus genomes from Europe reveal genomic and phenotypic variability during the 1918 pandemic

2021-05-14

Abstract excerpt

The 1918 influenza pandemic was the deadliest respiratory pandemic of the 20th century and determined the genomic make-up of subsequent human influenza A viruses (IAV). Here, we analyze the first 1918 IAV genomes from Europe and from the first, milder wave of the pandemic. 1918 IAV genomic diversity is consistent with local transmission and frequent long-distance dispersal events and in vitro polymerase character...

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Literature Corpus work
e0f52de8-929b-5b24-8e4a-c7f175217c43
DOI
10.1101/2021.05.14.444134
Open publication

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Archival influenza virus genomes from Europe reveal genomic and phenotypic variability during the 1918 pandemicDOI 10.1101/2021.05.14.444134
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