Article

Primary intracranial sarcoma associated with DICER1-mutant: A case report and preclinical investigation

2024-10-15

Abstract excerpt

<title>Abstract</title> <p>Primary intracranial sarcoma (PIS) is a rare and aggressive pediatric brain tumor, which is partially associated with <italic>DICER1</italic> mutant. Although the molecular genetic characteristics of this tumor have previously been investigated, novel therapeutic targets remain unclear. Further, the lack of faithful preclinical models has hampered the development of novel therapeutic st...

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Literature Corpus work: e08e12ea-9089-51d1-bd92-8838a92ae232
DOI: 10.21203/rs.3.rs-4835625/v1

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