Article

KDS2010, a newly developed reversible MAO-B inhibitor, as an effective therapeutic candidate for Parkinson’s disease

2020-07-07

Abstract excerpt

<h4>Background and Purpose</h4> Monoamine oxidase-B (MAO-B) is a long-standing therapeutic target for Parkinson’s disease (PD), however, previous clinical studies demonstrated discouraging effects of currently available irreversible MAO-B inhibitors. Since KDS2010, a novel, potent, selective, and reversible MAO-B inhibitor, has been developed, here we tested its therapeutic potential in animal models of PD. <h4>E...

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Literature Corpus work: dff67ac8-6386-51c2-b50d-b561c89d8246
DOI: 10.1101/2020.07.06.190579

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