Article

RESCUE: An end-to-end multi-agent LLM system for proactive rare-disease patient screening in the EHR

2026-07-01

Abstract excerpt

<h4>Background</h4> Rare diseases affect a significant portion of the global population, yet patients often endure a lengthy diagnostic odyssey, frequently missing the opportunity for timely diagnoses with exome or genome sequencing (ES/GS). Existing informatics tools often rely on pre-identified patients or rigid, institution-specific rule sets, failing to address the broader operational question of clinical uti...

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Literature Corpus work: df236b4d-a72c-5c04-a369-0b97ec8403da
DOI: 10.64898/2026.06.24.26356357

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