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Rapid Generation of Medical Countermeasure Candidates Via Computational Variation Analysis

2019-04-09

Abstract excerpt

Rapid responses to emerging infectious diseases are needed for viral and bacterial pathogens. For some pathogens, no medical countermeasures (MCMs) yet exist. Pathogen heterogeneity and antigenic variation lead to immune response escape mutations for some pathogens (e.g., influenza) limiting the effectiveness of medical countermeasures. High throughput sequencing enables characterization of large numbers of pathog...

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Literature Corpus work
def60ce2-4ddf-5583-8469-77f5b274da9b
DOI
10.1101/604256
Open publication

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Rapid Generation of Medical Countermeasure Candidates Via Computational Variation AnalysisDOI 10.1101/604256
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