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A phase I study of C-CAR088, a novel humanized anti-BCMA CAR T cell therapy in relapsed/refractory multiple myeloma

2022-03-22

Abstract excerpt

<h4>Background: </h4> Anti-B-cell maturation antigen (BCMA) chimeric antigen receptor-T cell (CAR T) therapy shows remarkable efficacy in patients with relapsed or refractory multiple myeloma (RRMM). C-CAR088, a novel second-generation humanized anti-BCMA CAR T cell therapy, was developed. <h4>Methods: </h4> This phase I dose-escalation and expansion study assessed the safety and efficacy of three dosages of C-CAR...

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Literature Corpus work
def5fbe4-d6c1-5827-a334-3ad72310760e
DOI
10.21203/rs.3.rs-1468511/v1
Open publication

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A phase I study of C-CAR088, a novel humanized anti-BCMA CAR T cell therapy in relapsed/refractory multiple myelomaDOI 10.21203/rs.3.rs-1468511/v1
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