Article

Human enteric viruses shape disease phenotype through divergent innate immunomodulation

2021-10-15

Abstract excerpt

<h4>Summary</h4> Altered enteric microorganisms in concert with host genetics shape inflammatory bowel disease (IBD) phenotypes. However, insight is limited to bacteria and fungi. We found virus like particles (VLPs) enriched from normal human colon resections, containing eukaryotic viruses and bacteriophages (collectively, the virome), actively elicited atypical anti-inflammatory innate immune programs. Converse...

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Literature Corpus work: deeb3efd-21c6-5aaa-ae99-418a4a5c38dc
DOI: 10.1101/2021.10.14.464404

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