Article
Multiomics Reveals Alterations in the Gut Microbiome, Host Proteins, and Host Metabolites Correlating with SADS-CoV Pathogenicity and the Immune Response in Piglets
2024-09-19
Abstract excerpt
<title>Abstract</title> <p>SADS-CoV, a coronavirus, is known to induce swine acute diarrhea syndrome. To explore the differences and commonalities in the pathogenesis mechanisms between highly pathogenic and low-pathogenic strains of SADS-CoV, we conducted an integrated analysis comprising proteomics, metabolomics, and short-chain fatty acid (SCFA) analysis, along with 16S rRNA sequencing of intestinal mucosa and...
Topics
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- Animal Virus Infections Studies
- Clostridium difficile and Clostridium perfringens research
- Gut microbiota and health
- Mycobacterium research and diagnosis
- Probiotics and Fermented Foods
- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
Identifiers and source
- Literature Corpus work
- dec83410-de33-5fa9-99ae-e49fdf801253
- DOI
- 10.21203/rs.3.rs-4839968/v1
