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Gut microbiota contributes to protection against porcine deltacoronavirus infection in piglets by modulating intestinal barrier and microbiome

6 Apr 2025

Abstract excerpt

BACKGROUND: Gut microbiota plays a critical role in counteracting enteric viral infection. Our previous study demonstrated that infection of porcine deltacoronavirus (PDCoV) disturbs gut microbiota and causes intestinal damage and inflammation in piglets. However, the influence of gut microbiota on PDCoV infection remains unclear. RESULTS: Firstly, the relationship between gut microbiota and disease severity of...

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PMID: 40189556
DOI: 10.1186/s40168-025-02092-z

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