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Point-of-Care Solid-Phase PCR in Vertical Microfluidic Chip Integrated with All-Dielectric Nanostructured Metasurface for Highly -Sensitive, Multiplexed Pathogen Detection

2025-05-25

Abstract excerpt

Multiplexed solid-phase polymerase chain reaction (SP-PCR) has emerged as an indispensable modality for concurrent amplification of multiple genetic loci within a singular reaction vessel, facilitating efficient molecular diagnostics. Nevertheless, SP-PCR has seldom been integrated into point-of-care diagnostic devices due to several technical challenges, such as bubble formation during PCR, long reaction time and...

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Literature Corpus work: de754411-3ff8-5433-90ed-40ad02821498
DOI: 10.1101/2025.05.24.25328289

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