Article

Engineered reporter phages for rapid detection of <i>Escherichia coli, Klebsiella</i> spp., and <i>Enterococcus</i> spp. in urine

2022-11-23

Abstract excerpt

The rapid detection and species-level differentiation of bacterial pathogens facilitates antibiotic stewardship and improves disease management. Here, we develop a rapid bacteriophage-based diagnostic assay to detect the most prevalent pathogens causing urinary tract infections: Escherichia coli, Klebsiella spp., and Enterococcus spp. For each uropathogen, two virulent phages were genetically engineered to expre...

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Literature Corpus work: dd972de8-bfad-50de-a34c-08ffdd44b5ce
DOI: 10.1101/2022.11.23.517494

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