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Time-to-event modeling with multimodal clinical and genetic features improves risk stratification of liver complications in chronic hepatitis C

2026-03-09

Abstract excerpt

Chronic hepatitis C (CHC) remains a leading cause of cirrhosis, hepatocellular carcinoma (HCC), and premature mortality despite effective antiviral therapy, underscoring the need for individualized risk stratification beyond fibrosis stage alone. Using harmonized data from the All of Us Research Program, we developed and internally validated an interpretable multimodal survival framework to predict incident cirrho...

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Literature Corpus work
dd1ec366-2795-5c3e-a603-0c3fc846a76b
DOI
10.64898/2026.03.06.26347819
Open publication

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