Functional investigation and two-sample Mendelian randomization study of bladder cancer-related genes: focus on gender differences

Abstract excerpt

<h4>Objective: </h4> Bladder cancer is a common malignant tumor. There is a significant gender difference in the incidence rate, and the pathogenesis has not yet been clarified. The objective of this study was to explore the potential pathogenic genes of bladder cancer, measure the expression of these genes in patients of different sexes, and apply these genes to predict the risk of bladder cancer in clinical prac...

Topics

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• Cell Proliferation
• Gene Expression Regulation, Neoplastic
• Mendelian Randomization Analysis
• Quantitative Trait Loci
• Single-Cell Analysis
• Single-Cell Gene Expression Analysis
• Transcriptome
• Urinary Bladder Neoplasms

Identifiers and source

Literature Corpus work

dd0d0358-50bc-5cdc-90fe-bfe45a087512

DOI

10.21203/rs.3.rs-3477859/v1