Acute myeloid leukemia expresses a specific group of olfactory receptors

Abstract excerpt

<h4>ABSTRACT</h4> Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults. Although new drugs for specific molecular subsets of AML have recently emerged, the 5-year overall survival rate is still approximately 25%. The treatment options for AML have remained stagnant for decades, and novel molecular targets for this disease are needed. Olfactory receptors (ORs) are seven transmembrane G-...

Topics

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• Acute Myeloid Leukemia Research
• Aged, 80 and over
• Chemokine receptors and signaling
• Histone Deacetylase Inhibitors Research
• Immune cells in cancer
• Olfactory and Sensory Function Studies
• Protein Degradation and Inhibitors
• Receptor Mechanisms and Signaling

Identifiers and source

Literature Corpus work

dc75f334-48dc-5b56-8cac-263cd100150e

DOI

10.1101/2022.04.12.488071