Article

ME/CFS and PASC Patient-Derived Immunoglobulin Complexes Disrupt Mitochondrial Function and Alter Inflammatory Marker Secretion

2025-08-10

Abstract excerpt

<h4>ABSTRACT</h4> Autoimmunity is a key clinical feature in both post-infectious Myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) and Post-Acute Sequelae of COVID (PASC). Passive transfer of immunoglobulins from patients’ sera into mice induces some clinical features of PASC. IgG-induced transfer of disease phenotypes has long been appreciated, yet the exact mechanism of disease development remains l...

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Literature Corpus work: dc16ddc1-1f37-55d0-8705-88b448517143
DOI: 10.1101/2025.08.06.25332978

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