Article

Humanized Kcnv2 E151X Mouse Captures Hallmarks of KCNV2-Associated Retinal Dystrophy

2026-01-05

Abstract excerpt

<h4>Background</h4> KCNV2-associated retinopathy is a rare inherited retinal dystrophy caused by variants in the KCNV2 gene, leading to disrupted photoreceptor function and slowly progressive vision loss. Patients have characteristic electroretinography abnormalities, including reduced cone responses, delayed and reduced rod responses to low light flashes and paradoxally large rod-driven responses to bright flash...

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Literature Corpus work: db1ae91e-f4c8-55ef-b733-087031cd3f20
DOI: 10.64898/2026.01.05.697593

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