Article

Infection-Induced Extracellular Vesicles Evoke Neuronal Transcriptional and Epigenetic Changes

2020-11-27

Abstract excerpt

<h4>ABSTRACT</h4> Infection with the protozoan Toxoplasma gondii induces changes in neurotransmission, neuroinflammation, and behavior, yet it remains elusive how these changes come about. In this study we investigated how norepinephrine levels are altered by infection. TINEV (Toxoplasma-induced neuronal extracellular vesicles) isolated from infected noradrenergic cells down-regulated dopamine β-hydroxylase ( D...

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Literature Corpus work: daf6faf6-7d85-54f3-8997-ed87165c8ecf
DOI: 10.1101/2020.11.26.399345

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