Article

Immunopeptidomic analysis of influenza A virus infected human tissues identifies internal proteins as a rich source of HLA ligands

2021-08-17

Abstract excerpt

CD8+ and CD4+ T cells provide cell-mediated cross-protection against multiple influenza strains by recognising epitopes bound as peptides to human leukocyte antigen (HLA) class I and -II molecules respectively. Two challenges in identifying the immunodominant epitopes needed to generate a universal T cell influenza vaccine are: A lack of cell models susceptible to influenza infection which present population-preva...

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Literature Corpus work: daaa15c5-0cb9-510a-9184-61db583ec5f7
DOI: 10.1101/2021.08.17.456620

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Immunopeptidomic analysis of influenza A virus infected human tissues identifies internal proteins as a rich source of HLA ligandsDOI 10.1101/2021.08.17.456620Read

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