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The optimal 18F-Fluoromisonidazole PET threshold to define tumor hypoxia in preclinical squamous cell carcinomas using pO2 electron paramagnetic resonance imaging as reference truth.

2022-03-11

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<title>Abstract</title> <p>Purpose : To identify the optimal threshold in 18 F-Fluoromisonidazole (FMISO) PET images to accurately locate tumor hypoxia by using electron paramagnetic resonance imaging (pO 2 EPRI) as ground truth for hypoxia, defined by pO 2 ≤10mmHg. <h4>Methods:</h4> Tumor hypoxia images in mouse models of SCCVII squamous cell carcinoma (n=16) were acquired in a hybrid PET/EPRI imaging system two...

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Literature Corpus work
da04160d-f032-509a-84c2-46b718dd3686
DOI
10.21203/rs.3.rs-1388908/v1
Open publication

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The optimal 18F-Fluoromisonidazole PET threshold to define tumor hypoxia in preclinical squamous cell carcinomas using pO2 electron paramagnetic resonance imaging as reference truth.DOI 10.21203/rs.3.rs-1388908/v1
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