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A novel <i>qacA</i> allele results in an elevated chlorhexidine glu conate minimum inhibitory concentration in cutaneous <i>Staphylococcus epidermidis</i> isolates

2018-12-09

Abstract excerpt

Chlorhexidine gluconate (CHG) is a topical antiseptic widely used in healthcare settings. In Staphylococcus spp., the pump QacA effluxes CHG, while the closely related QacB cannot due to a single amino acid substitution. We characterized 1,050 cutaneous Staphylococcus isolates obtained from 173 pediatric oncology patients enrolled in a multicenter CHG bathing trial. CHG susceptibility testing revealed 63 (6%) of...

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Literature Corpus work
d9fec7a1-1dc1-55a1-a1d9-5f5dfc3664fe
DOI
10.1101/490805
Open publication

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A novel <i>qacA</i> allele results in an elevated chlorhexidine glu conate minimum inhibitory concentration in cutaneous <i>Staphylococcus epidermidis</i> isolatesDOI 10.1101/490805
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