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Analysis on Distribution and Genomic Diversity of High-Level Antiseptic Resistance Genes qacA and qacB in Human Clinical Isolates of Staphylococcus aureus

1 Jun 2003

Abstract excerpt

High-level antiseptic resistance of Staphylococcus aureus is mediated by multidrug efflux pumps encoded by qacA and qacB genes. We investigated distribution and genomic diversity of these antiseptic resistance genes in a total of 522 clinical strains of S. aureus isolated recently in a Japanese hospital. The qacA/B gene was detected in 32.6% of methicillin-resistant S. aureus (MRSA) and 7.5% of...

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PMID: 12820795
DOI: 10.1089/107662903765826697

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