Article

Biomechanical control of meiotic chromosomal bouquet and germ cell morphogenesis by the zygotene cilium

2021-02-09

Abstract excerpt

The hallmark of meiosis is chromosomal pairing and synapsis via synaptonemal complexes, but chromosomal pairing also depends on cytoplasmic counterparts that tether and rotate telomeres on the nuclear envelope. Telomeres slide on perinuclear microtubules, shuffling chromosomes and mechanically driving their homology searches. Pull of telomeres towards the centrosome drives formation of the “zygotene chromosomal bo...

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Literature Corpus work: d9ad11fd-711e-563c-bb6c-f35b3e8be7f6
DOI: 10.1101/2021.02.08.430249

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