Article

Neural dynamics underlying the persistence of perseverative thought in depression and anxiety

2025-07-25

Abstract excerpt

Depression and anxiety are characterized by transdiagnostic symptoms, including perseverative thought: a class of thoughts such as rumination and worry that are negative, repetitive, and difficult to control. These thoughts contribute to substantial distress, poor treatment response, and increased risk of relapse. What makes perseverative thoughts persevere? Using task-based fMRI, we compared how adults with no li...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d8e1276e-c000-57bd-bfe4-7f3468f9bfe8
DOI: 10.1101/2025.07.21.666019

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Neural dynamics underlying the persistence of perseverative thought in depression and anxietyDOI 10.1101/2025.07.21.666019Read

Neural dynamics underlying the persistence of perseverative thought in depression and anxietySemantic proximity Read

Neural dynamics underlying the persistence of perseverative thought in depression and anxietySemantic proximity Read

Neural Correlates of Sustained Attention During Disengagement From Repetitive ThoughtSemantic proximity Read

Neural dynamics of spontaneous memory recall and future thinking in the continuous flow of thoughtsSemantic proximity Read

Brain Mechanisms Underlying the Inhibitory Control of ThoughtSemantic proximity Read

Flexible brain state engagement predicts cognitive control transdiagnosticallySemantic proximity Read

Limited generalizability of dynamic fMRI correlates of adolescent ruminationSemantic proximity Read

Uncovering the embodied dimension of the wandering mindSemantic proximity Read

Neural Mechanisms of Mindful Disengagement from WorrySemantic proximity Read

Neurocomputational mechanisms underlying emotional awareness: insights afforded by deep active inference and their potential clinical relevanceSemantic proximity Read

Ongoing thoughts at rest reflect functional brain organization and behaviorSemantic proximity Read

Generalizable prediction of stimulus-independent, task-unrelated thought from functional brain networksSemantic proximity Read