Article

Global variation in the SARS-CoV-2 proteome reveals the mutational hotspots in the drug and vaccine candidates

2020-07-31

Abstract excerpt

<h4>ABSTRACT</h4> To accelerate the drug and vaccine development against the severe acute respiratory syndrome virus 2 (SARS-CoV-2), a comparative analysis of SARS-CoV-2 proteome has been performed in two phases by considering manually curated 31389 whole genome sequences from 84 countries. Among the 9 mutations that occur at a high significance (T85I-NPS2, L37F-NSP6, P323L-NSP12, D614G-spike, Q57H-ORF3a, G251V-O...

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Literature Corpus work: d8c72834-34d6-5267-8169-3519531bf904
DOI: 10.1101/2020.07.31.230987

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