Article

PRRI: Plasmid Resistance Risk Index Prioritizing Clinically Relevant Plasmid-Associated Antimicrobial Resistant Genes in the Human Gut

2026-08-31

Abstract excerpt

<title>Abstract</title> <p>The human gut microbiome is a major reservoir of antimicrobial resistance genes (ARGs), but metagenomic studies typically describe resistomes by abundance rather than clinical relevance. This limitation is especially important for plasmid-associated ARGs, which have greater dissemination potential through horizontal transfer. We developed the Plasmid Resistance Risk Index (PRRI), an int...

Identifiers and source

Literature Corpus work: d7fc11f4-f9f6-5dad-96cb-a5a2fa3c176f
DOI: 10.21203/rs.3.rs-10470568/v1

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