Bilirubin and the Genome: The Hereditary Basis of Unconjugated Neonatal Hyperbilirubinemia.

Abstract excerpt

Severe neonatal unconjugated hyperbilirubinemia, with the risk of bilirubin encephalopathy or kernicterus in severe, untreated cases, occurs when bilirubin production exceeds the body's ability to eliminate it. The causes of neonatal hyperbilirubinemia are multifactorial and comprise increased hemolysis on the one hand, and diminished bilirubin conjugation on the other. In recent years, many of these etiologies ha...

Topics

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• Heme Oxygenase-1 and Carbon Monoxide
• Methemoglobinemia and Tumor Lysis Syndrome
• Neonatal Health and Biochemistry

Identifiers and source

Literature Corpus work

d7f5cdb6-5ce4-5df8-be42-48579ba392ac

DOI

10.2174/1570160053174992