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Human UDP-glucuronosyl transferases: chemical defence, jaundice and gene therapy.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Nov 1993

Brierley C H, Burchell B

Abstract excerpt

Human UDP-glucuronosyltransferases (UDPGTs) are a family of enzymes which detoxify many hundreds of compounds by their conjugation to glucuronic acid, rendering them both harmless and more water soluble, hence, excretable. The level of expression of each UDPGT isoform in the body is the result of interplay between temporal, tissue-specific and environmental regulators. This complexity contributes to the...

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PMID: 8292005
DOI: 10.1002/bies.950151108

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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