Multi-omics analysis of mouse fecal microbiome reveals supplier-dependent functional differences and novel metagenome-assembled genomes

Abstract excerpt

Host genetics, sex, and other within-source factors have been associated with characteristic effects on the fecal microbiome in mice, however, the commercial source of mice remains the dominant factor. Increasing evidence indicates that supplier-specific microbiomes in particular confer differences in disease susceptibility in models of inflammatory conditions, as well as baseline behavior and body morphology. How...

Topics

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• Barrier Structure and Function Studies
• Clostridium difficile and Clostridium perfringens research
• Congenital gastrointestinal and neural anomalies
• Dietary Effects on Health
• Epigenetics and DNA Methylation
• Gastrointestinal motility and disorders
• Gut microbiota and health
• Probiotics and Fermented Foods

Identifiers and source

Literature Corpus work

d7ed319f-5681-5498-83b1-4e190feba7cf

DOI

10.1101/2022.09.12.507288