MRGM: a mouse reference gut microbiome reveals a large functional discrepancy for gut bacteria of the same genus between mice and humans

Abstract excerpt

<h4>ABSTRACT</h4> The gut microbiome is associated with human diseases and interacts with dietary components and drugs. In vivo mouse models may be effective for studying diet and drug effects on the gut microbiome. We constructed a mouse reference gut microbiome (MRGM, https://www.mbiomenet.org/MRGM/ ) that includes newly-assembled genomes from 878 metagenomes. Leveraging samples with ultra-deep metagenomic se...

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• Cannabis and Cannabinoid Research
• Clostridium difficile and Clostridium perfringens research
• Diet and metabolism studies
• Diet, Metabolism, and Disease
• Epigenetics and DNA Methylation
• Gastrointestinal motility and disorders
• Gut microbiota and health
• Probiotics and Fermented Foods

Identifiers and source

Literature Corpus work

1cc48489-2e48-5bdb-a134-c7fe62955563

DOI

10.1101/2021.10.24.465599