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Glycoproteogenomics characterizes the CD44 splicing code driving bladder cancer invasion

2021-09-06

Abstract excerpt

Bladder cancer (BC) management demands the introduction of novel molecular targets for precision medicine. Cell surface glycoprotein CD44 has been widely studied as a potential biomarker of BC aggressiveness and cancer stem cells. However, significant alternative splicing and multiple glycosylation generate a myriad of glycoproteoforms with potentially distinct functional roles. The lack of tools for precise molec...

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Literature Corpus work
d7ad7a1f-fc06-5afe-b380-78221dde17f1
DOI
10.1101/2021.09.04.458979
Open publication

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Glycoproteogenomics characterizes the CD44 splicing code driving bladder cancer invasionDOI 10.1101/2021.09.04.458979
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