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W246G Mutant ELOVL4 Impairs Synaptic Plasticity in Parallel and Climbing Fibers and Causes Motor Defects in a Rat Model of SCA34

2021-02-15

Abstract excerpt

<title>Abstract</title> <p>Spinocerebellar ataxias (SCA) are a group of neurodegenerative disorders caused by a number of different mutations the leads to loss of motor coordination with characteristic ages of onset, symptomatology, and rates of progression. SCA type 34 (SCA34) is an age-related cerebellar neurodegenerative disorder caused by mutations in the <italic>Fatty Acid Elongase-4</italic> (<italic>ELOVL4...

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Literature Corpus work: d7938b94-4877-5b9f-a658-acfb1fdaabd4
DOI: 10.21203/rs.3.rs-145817/v2

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W246G Mutant ELOVL4 Impairs Synaptic Plasticity in Parallel and Climbing Fibers and Causes Motor Defects in a Rat Model of SCA34DOI 10.21203/rs.3.rs-145817/v2Read

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