Article

First detection of pfhrp2 and pfhrp3 gene deletions in Niger Republic: a retrospective sub- analysis of biological samples

2026-04-26

Abstract excerpt

<title>Abstract</title> Background Rapid diagnostic tests (RDTs) based on histidine-rich protein 2 (HRP2) are the main diagnostic tool for malaria in Niger and many countries in sub-Saharan Africa. However, deletions of the <italic>P. falciparum hrp2</italic> and <italic>hrp3</italic> genes can compromise RDT performance, and pose a threat to diagnostic accuracy. Although these deletions were reported i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d769f1ab-800c-57b1-98f0-8d1acd88fa0c
DOI: 10.21203/rs.3.rs-9407357/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

First detection of pfhrp2 and pfhrp3 gene deletions in Niger Republic: a retrospective sub- analysis of biological samplesDOI 10.21203/rs.3.rs-9407357/v1Read

Emergence of pfhrp2 and pfhrp3 Gene Deletions in Plasmodium falciparum and Diagnostic Challenges in BangladeshSemantic proximity Read

Plasmodium falciparum withpfhrp2/3deletion not detected in a 2018-2021 malaria longitudinal cohort study in Kinshasa Province, Democratic Republic of the CongoSemantic proximity Read

High prevalence of pfhrp2 and pfhrp3 gene deletions and major threat to malaria control programs in EthiopiaSemantic proximity Read

Prevalence of Plasmodium falciparum parasites with Pfhrp2 exon 2 gene deletion in symptomatic malaria patients across Ghana in 2021Semantic proximity Read

Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions among patients in the DRC enrolled from 2017 to 2018Semantic proximity Read

Deletions of the Plasmodium falciparum pfhrp2 and pfhrp3 genes among patients enrolled at six locations in the DRC: 2017–2018Semantic proximity Read

Detection of Plasmodium falciparum harbouring pfhrp2 deletions in six border states of SudanSemantic proximity Read

First report of pfhrp2 and pfhrp3 gene deletions compromising HRP2-based malaria rapid diagnostic tests in MalawiSemantic proximity Read

Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions from Persons with Symptomatic Malaria Infection in Ethiopia, Kenya, Madagascar, and RwandaSemantic proximity Read

Prevalence of Plasmodium falciparum Isolates Lacking the Histidine Rich Protein 2 Gene Among Symptomatic Malaria Patients in Kwilu Province, DR. Congo.Semantic proximity Read

Malaria Rapid Diagnostic Tests: very low prevalence of Plasmodium falciparum histidine-rich protein 2 (pfhrp2) deletion in the Brazil-Venezuela-Guyana tri-borderSemantic proximity Read

Plasmodium falciparum Histidine-Rich Protein 2 and 3 Gene Deletions in Strains from Nigeria, Sudan, and South SudanSemantic proximity Read