Article

First report of pfhrp2 and pfhrp3 gene deletions compromising HRP2-based malaria rapid diagnostic tests in Malawi

2025-05-16

Abstract excerpt

<title>Abstract</title> <p>Background HRP2-based rapid diagnostic tests (RDTs) are widely used for malaria diagnosis in Malawi, but their accuracy may be compromised by <italic>Plasmodium falciparum</italic> parasites lacking the <italic>pfhrp2</italic> and <italic>pfhrp3</italic> genes. While such deletions have been reported in other malaria-endemic countries, their presence and diagnostic impact in Malawi rem...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3bb83988-3502-53d5-9b31-3ce31b9cb453
DOI: 10.21203/rs.3.rs-6618930/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

First report of pfhrp2 and pfhrp3 gene deletions compromising HRP2-based malaria rapid diagnostic tests in MalawiDOI 10.21203/rs.3.rs-6618930/v1Read

Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions among patients enrolled at 100 health facilities throughout Tanzania: February to July 2021Semantic proximity Read

Molecular surveillance of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Mozambique, 2023Semantic proximity Read

Plasmodium falciparum with pfhrp2 and pfhrp3 gene deletions in asymptomatic malaria infections in the Lake Victoria region, KenyaSemantic proximity Read

<i>Plasmodium falciparum w</i>ith<i>pfhrp2/3</i>deletion not detected in a 2018-2021 malaria longitudinal cohort study in Kinshasa Province, Democratic Republic of the CongoSemantic proximity Read

Community-based surveys for Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions in selected regions of mainland TanzaniaSemantic proximity Read

First detection of pfhrp2 and pfhrp3 gene deletions in Niger Republic: a retrospective sub- analysis of biological samplesSemantic proximity Read

<i>Plasmodium falciparum pfhrp2</i>and<i>pfhrp3</i>gene deletions among patients enrolled at 100 health facilities throughout Tanzania: February to July 2021Semantic proximity Read

Malaria Prevalence, Associated Risk factors, and Molecular Surveillance of Plasmodium falciparum hrp2/hrp3 Gene Deletions in Northern UgandaSemantic proximity Read

Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions among patients in the DRC enrolled from 2017 to 2018Semantic proximity Read

Emergence of pfhrp2 and pfhrp3 Gene Deletions in Plasmodium falciparum and Diagnostic Challenges in BangladeshSemantic proximity Read

Limited threat of Plasmodium falciparum pfhrp2 and pfhrp3 gene deletion to the utility 1 of HRP2-based malaria RDTs in Northern UgandaSemantic proximity Read

Deletions of the Plasmodium falciparum pfhrp2 and pfhrp3 genes among patients enrolled at six locations in the DRC: 2017–2018Semantic proximity Read