Article

Apoptosis induction in ascorbic acid treated human colorectal cancer cell lines (Caco-2)

2025-01-02

Abstract excerpt

The current study aims to study the therapeutic effects of ascorbic acid on Caco-2 cancer cell inhibitory mechanisms. The cytotoxicity of ascorbic acid on Caco-2 cells was determined by MTT and LDH assays. Also, apoptosis induction in ascorbic acid-treated Caco-2 cells was tested through annexin and DNA fragmentation techniques. Cell cycle arrest, ROS generation, RT-PCR, and western plot analyses were conducted to...

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Literature Corpus work: d70908dc-8f34-5e2e-88e2-705796785f90
DOI: 10.1080/22311866.2025.2465679

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