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Article

SARS-CoV-2 and its variants, but not Omicron, induces thymic atrophy and impaired T cell development

2022-04-08

Abstract excerpt

Pathogenic infections cause thymic atrophy, perturb thymic-T cell development and alter immunological response. Previous studies reported dysregulated T cell function and lymphopenia in coronavirus disease-19 (COVID-19) patients. However, immune-pathological changes, in the thymus, post severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection have not been elucidated. Here, we report SARS-CoV-2 infec...

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Identifiers and source

Literature Corpus work
d6d83f61-c667-5db5-ac3b-7268179da820
DOI
10.1101/2022.04.07.487556
Open publication

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