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Article

Behavioral biomarker reliability can mislead mechanistic inference in precision psychiatry

2026-07-04

Abstract excerpt

<p>Psychological tasks are increasingly used to develop behavioral biomarkers for precision psychiatry, yet poor test-retest reliability of many task-derived summary measures has raised doubts about their use for stratifying patients, predicting treatment response or indexing clinically relevant mechanisms. In simulations of a fear-conditioning task, we establish two results. First, common summaries can mislead in...

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Literature Corpus work
d61991fa-974d-5195-8ac1-e516b52e4ced
DOI
10.31234/osf.io/dg75a_v1
Open publication

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Behavioral biomarker reliability can mislead mechanistic inference in precision psychiatryDOI 10.31234/osf.io/dg75a_v1
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