Article

Brain Region-Specific Gene Co-expression Networks Reveal Neuroinflammation and ER Stress Signatures in Major Depressive Disorder

2025-06-22

Abstract excerpt

This study aims to investigate gene expression changes in different brain regions of Major Depressive Disorder (MDD) patients using transcriptomics and bioinformatics approaches. Through differential expression gene (DEG) analysis, functional enrichment analysis, and Weighted Gene Co-expression Network Analysis (WGCNA), we aimed to identify key genes, pathways, and co-expression modules associated with MDD, with p...

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Literature Corpus work: d5fb7b8a-cd74-533e-b4f2-b7d983a989eb
DOI: 10.1101/2025.06.18.660280

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