Article

Helicobacter pylori diversity and gastro-duodenal disease in Western Africa

2020-01-01

Abstract excerpt

Helicobacter pylori (Hp) is causally linked with gastric pre-malignant lesions, gastric cancer (GCA) and peptic ulcer disease (PUD). In Africa, PUD is prevalent while GCA has reportedly low incidence. Less is known about pre-malignant lesions. Hp genes cagA and vacA are established virulence factors and have been associated with increased gastroduodenal disease (GDD) risk. Further, diversity in the Carboxyl-termin...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d5365333-02ee-52e2-b2fb-59e6e10fbdc7
DOI: 10.25392/leicester.data.14587659.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Helicobacter pylori diversity and gastro-duodenal disease in Western AfricaDOI 10.25392/leicester.data.14587659.v1Read

Helicobacter pylori cagA and vacA genes in dyspeptic Ghanaian patients.Semantic proximity Read

Distribution of Helicobacter pylori virulence markers in patients with gastroduodenal diseases in Pakistan.Semantic proximity Read

Helicobacter pyloriInfection, Virulence Genes’ Distribution and Accompanying Clinical Outcomes: The West Africa SituationSemantic proximity Read

Heterogeneity in the Helicobacter pylori vacA and cagA genes: association with gastroduodenal disease in South Africa?Semantic proximity Read

Evolutionary History of the Helicobacter pylori Genome: Implications for Gastric CarcinogenesisSemantic proximity Read

Helicobacter pylori patient isolates from South Africa and Nigeria differ in virulence factor pathogenicity profile and associated gastric disease outcome.Semantic proximity Read

Prevalence, diversity and disease association of Helicobacter pylori in dyspeptic patients from Pakistan.Semantic proximity Read

Gastric cancer in Africa: what do we know about incidence and risk factors?Semantic proximity Read

Detection of Helicobacter pylori and its virulence genes (cagA, dupA, and vacA) among patients with gastroduodenal diseases in Chris Hani Baragwanath Academic Hospital, South AfricaSemantic proximity Read

Helicobacter pylori endemic and gastric disease.Semantic proximity Read

Clinical relevance of cagA and vacA gene polymorphisms in Helicobacter pylori isolates from Senegalese patients.Semantic proximity Read

Profile of Helicobacter pylori cagA &vacA genotypes and its association with the spectrum of gastroduodenal disease.Semantic proximity Read