Article

Non-consanguineous pediatric myelofibrosis due to MPIG6B mutations in a patient of European ancestry

2022-05-28

Abstract excerpt

Myelofibrosis (MF) in the pediatric setting is uncommon and appears to be pathogenically heterogeneous. MF due to intrinsic bone marrow abnormality (IMF) is distinct from adult-type Primary myelofibrosis (PMF) as they can lack the common genetic markers of clonality. To date, all but two reported patients with pediatric MF and mutated MPIG6B have been Arabic, and all reported cases have had a family history of con...

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Literature Corpus work: d46a52f9-dd52-5649-951c-0964cdaffcbe
DOI: 10.22541/au.165371405.59245002/v1

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