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Article

Infantile Myelofibrosis and Myeloproliferation with CDC42 Dysfunction.

Journal of clinical immunology - 1 May 2020

Verboon Jeffrey M, Mahmut Dilnar, Kim Ah Ram, Nakamura Mitsutoshi, Abdulhay Nour J, Nandakumar Satish K, Gupta Namrata, Akie Thomas E, Geddis Amy E, Manes Becky, Kapp Meghan E, Hofmann Inga, Gabriel Stacey B, Klein Daryl E, Williams David A, Frangoul Haydar A, Parkhurst Susan M, Crane Genevieve M, Cantor Alan B, Sankaran Vijay G

Abstract excerpt

Studies of genetic blood disorders have advanced our understanding of the intrinsic regulation of hematopoiesis. However, such genetic studies have only yielded limited insights into how interactions between hematopoietic cells and their microenvironment are regulated. Here, we describe two affected siblings with infantile myelofibrosis and myeloproliferation that share a common de novo mutation in the Rho GTPase...

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Identifiers

PMID: 32303876
DOI: 10.1007/s10875-020-00778-7
PMCID: PMC7253386

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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