Voice Abnormalities in Patients with Mucopolysaccharidosis: Can They Serve as Biological Markers for Early Diagnosis and Disease Progression?

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Mucopolysaccharidoses (MPS) are a group of genetic lysosomal storage disorders caused by deficiencies or malfunctions in enzymes responsible for breaking down glycosaminoglycans (GAGs). Ear nose throat (ENT) disorders are very common in individuals with MPS, particularly in types I, II, and VI, and are often some of the early symptoms. The main purpose of this s...

Topics

Open a Topic to create a Post that cites this publication.

• Carbohydrate Chemistry and Synthesis
• Disease Models, Animal
• Early Diagnosis
• Hearing Loss
• Iduronidase
• Lysosomal Storage Disorders Research
• Mucopolysaccharidosis I
• Phenotype

Identifiers and source

Literature Corpus work

d3a3423c-f952-5fdc-b9e5-ad797dc5e17b

DOI

10.21203/rs.3.rs-6237773/v1