Article

Genetic modifiers of risk and age at onset in <i>GBA</i> associated Parkinson’s disease and Lewy body dementia

2019-08-18

Abstract excerpt

Parkinson’s disease (PD) is a genetically complex disorder. Multiple genes have been shown to contribute to the risk of PD, and currently 90 independent risk variants have been identified by genome-wide association studies. Thus far, a number of genes (including SNCA , LRRK2 , and GBA ) have been shown to contain variability across a spectrum of frequency and effect, from rare, highly penetrant variants to comm...

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Literature Corpus work: d3909158-40cd-5cf0-bb3b-098977f629bc
DOI: 10.1101/738351

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