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Using Culture-Enriched Phenotypic Metagenomics for Targeted High-Throughput Monitoring of the Clinically Important Fraction of the β-Lactam Resistome

5 Aug 2022

Abstract excerpt

High bacterial community diversity and complexity greatly challenge the cost-efficient monitoring of clinically prevalent antibiotic-resistant bacteria, which are usually present as rare and important populations involved in the environmental dissemination of clinical resistance. Here, we introduce culture-enriched phenotypic metagenomics that integrates culture enrichment, phenotypic screening, and metagenomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35930686
DOI: 10.1021/acs.est.2c03627

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