Article

microRNA-mRNA interaction identification in Wilms tumor using principal component analysis based unsupervised feature extraction

2016-06-16

Abstract excerpt

Wilms tumor is one of lethal child renal cancers, for which no known disease causing mechanisms exist. In this paper, we tried to identify possible disease causing microRNA(miRNA)-mRNA pairs (interactions) by analyzing (partially matched) miRNA/mRNA gene expression profiles with the recently proposed principal component analysis based unsupervised feature extraction. It successfully identified multiple miRNA-mRNA...

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Literature Corpus work: d384f3ca-39e7-5136-9907-ff712f1210e8
DOI: 10.1101/059295

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