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Article

Anakinra for dengue patients with hyperinflammation: protocol for a randomized double-blind placebo-controlled trial

2024-11-22

Abstract excerpt

<h4>Background: </h4> Novel host-directed therapies are urgently needed for patients with dengue, particularly those at high risk of developing severe disease. Broad immunosuppression using corticosteroids in unselected patients with dengue has so far been unsuccessful. Patients with hyperinflammation (raised CRP and/or ferritin levels) are at highest risk of poor outcomes in dengue. Anakinra is a licensed, bio-en...

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Literature Corpus work
d37d642e-4449-5f1c-8bb2-97b80eb1f115
DOI
10.12688/wellcomeopenres.21017.1
Open publication

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Anakinra for dengue patients with hyperinflammation: protocol for a randomized double-blind placebo-controlled trialDOI 10.12688/wellcomeopenres.21017.1
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