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Article

[Genetic analysis of three families affected with split-hand/split-foot malformation].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Aug 2017

He Wenbin, Lin Ge, Liang Ping, Cheng Dehua, Hu Xiao, Zhou Lihua, Xiong Bo, Tan Yueqiu, Lu Guangxiu, Li Wen

Abstract excerpt

OBJECTIVE: To explore the genetic etiology of three families affected with split-hand/split-foot malformation (SHFM). METHODS: Peripheral venous blood samples from 21 members of pedigree 1, 2 members of pedigree 2, and 2 members of pedigree 3 were collected. PCR-Sanger sequencing, microarray chip, fluorescence in situ hybridization (FISH), real-time PCR, and next-generation sequencing were employed to screen the...

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Share to Chromosomes, Human, Pair 10
Share to Foot Deformities, Congenital

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28777841
DOI: 10.3760/cma.j.issn.1003-9406.2017.04.002

Genes

LBX1
POLL
TLX1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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