Article

circPMS1-mediated LIM protein scaffolding promotes cytoskeletal remodeling and melanoma metastasis

2026-06-20

Abstract excerpt

Circular RNAs (circRNAs) have been implicated in diverse biological processes and diseases such as cancer; however, their functional roles in tumor biology remain incompletely understood. Here, we identify circPMS1 as an aberrantly upregulated, pro-metastatic circRNA in melanoma. Overexpression and silencing studies revealed that circPMS1 promotes migration and invasion of non-transformed melanocytes and melanom...

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Literature Corpus work: d3194134-69b3-5531-9979-60f2cd1ea5c1
DOI: 10.64898/2026.06.18.733219

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