Article

Evaluating biomarkers and prediction models with E2P Simulator

2026-01-12

Abstract excerpt

<p>Precision psychiatry aims to identify biomarkers and develop prediction models to improve diagnosis, prognosis, and treatment selection for mental illness. Despite extensive research, translating findings into clinically useful tools remains challenging. Here we argue that one key contributor to this translational gap is a pervasive misalignment between routine statistical analytic practices and the criteria fo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d2bfce75-6d4a-5796-8e88-7e3f9f1c3879
DOI: 10.31234/osf.io/atn5m_v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Evaluating biomarkers and prediction models with E2P SimulatorDOI 10.31234/osf.io/atn5m_v1Read

Evaluating biomarkers and prediction models with E2P SimulatorSemantic proximity Read

Integrating theory-driven and data-driven computational psychiatrySemantic proximity Read

B4-2: Risk Engine Evaluation Software: An Analytics Platform for Individualized GuidelinesSemantic proximity Read

A plasmode simulation-based bias analysis for residual confounding by unmeasured variables leveraging information-rich subsetsSemantic proximity Read

Beyond Step Count: Are We Ready to Use Digital Phenotyping to Make Actionable Individual Predictions in Psychiatry?Semantic proximity Read

High-Throughput Observational Evidence Generation Using Linked Electronic Health Record and Claims DataSemantic proximity Read

AutoPsychDx: An LLM Agent Framework for Automated Psychometric Diagnosis Using Multi-Method ClassificationSemantic proximity Read

AutoPsychDx: An LLM Agent Framework for Automated Psychometric Diagnosis Using Multi-Method ClassificationSemantic proximity Read

Beyond P-values: A Multi-Metric Framework for Robust Feature Selection and Predictive ModelingSemantic proximity Read

CauReL: Dynamic Counterfactual Learning for Precision Drug Repurposing in Alzheimer's DiseaseSemantic proximity Read

How Can I Stay Healthy? – Benchmarking Large Language Models for Personalized and Biomarker-Based Intervention RecommendationsSemantic proximity Read

ChatGPT-Enhanced ROC Analysis (CERA): A Shiny Web Tool for Finding Optimal Cutoff in Biomarker AnalysisSemantic proximity Read